MIDLINE CARCINOMA WITH T(15;19) AND BRD4-NUT FUSION ONCOGENE IN A 30-YEAR-OLD FEMALE WITH RESPONSE TO DOCETAXEL AND RADIOTHERAPY

Midline carcinoma with t(15;19) and BRD4-NUT fusion oncogene in a 30-year-old female with response to docetaxel and radiotherapy

Abstract Background Poorly differentiated midline carcinoma with a translocation between chromosomes 15 and 19, i.e.t(15;19), has been recognized as a distinct clinical entity for over a decade.This tumor affects young individuals, shows a rapidly fatal clinical course despite intensive therapy.The t(15;19) results in the fusion oncogene BRD4-NUT.I

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Light Robust Goal Programming

Robust goal programming (RGP) is an emerging field of research Inverter Wire in decision-making problems with multiple conflicting objectives and uncertain parameters.RGP combines robust optimization (RO) with variants of goal programming techniques to achieve stable and reliable goals for previously unspecified aspiration levels of the decision-ma

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Pattern of sucker development in cuttlefishes

Abstract Background Morphological novelties have been acquired through evolutionary processes and related to the adaptation of new life-history strategies with new functions of the bodyparts.Cephalopod molluscs such as octopuses, squids and cuttlefishes possess unique morphological characteristics.Among those novel morphologies, in particular, suck

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